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Research protocols

Every blueprint on this page is a theoretical research protocol. The compounds referenced are supplied for research purposes and are not approved medicines. Nothing here is medical advice or a recommendation for human use. Full disclaimer →

Protocol Blueprints

The Vault tells you what every compound does. A blueprint tells you which ones to run, in what order, for how long, and what to test — one choice per pathway, with the runner-up named so you can disagree with it.

Change how you look

The four people arrive for most.

The Fat Loss Blueprint
16 weeks, six pathways, one pick each

Fat loss is not one mechanism, which is why people stall. This blueprint attacks it on six fronts at once — appetite, mitochondrial output, direct lipolysis, insulin, thyroid substrate and lean-mass protection — because …

The Muscle & Strength Blueprint
20 weeks, six arms, one pick each

Muscle is the goal where the compounds matter least and people expect them to matter most. Training and protein do the overwhelming majority of the work, which is why the foundation on this page is not a formality. What…

The Skin & Hair Blueprint
16 weeks, five arms, one pick each

The single most useful thing to know in this category is the delivery ceiling: a molecule has to cross the stratum corneum before any of its biology matters, and size decides that. GHK-Cu is about 340 daltons and cro…

The Libido & Sexual Function Blueprint
Four arms — desire and function are not the same problem

Four separable systems, and the arm you need is decided by two questions you already know the answers to. Do you want to? If desire itself is absent, that is central — melanocortin and dopamine signaling — and no va…

Fix how you feel

Start here if something is actually wrong rather than merely unoptimized.

The Energy & Fatigue Blueprint
12 weeks, four arms, one pick each

Fatigue is the symptom with the highest ratio of boring causes to interesting ones, and this page is built around that fact. The fourth arm — iron, B12, thyroid, vitamin D — accounts for the majority of people who ar…

The Sleep Blueprint
8 weeks, four arms, one pick each

Onset, maintenance, depth and rhythm are four different problems with four different answers, and treating them as one is why most sleep supplements disappoint. If you cannot fall asleep, that is an onset problem. I…

The Mood & Stress Resilience Blueprint
Five arms — and the honest first step is a blood draw and a conversation

Low mood is a common endpoint of several different upstream problems, and this is the page where treating the wrong one wastes the most time. Your stress axis is stuck on — the HPA arm, where the complaint is wired-…

The Gut Health Blueprint
12 weeks, five arms, one pick each

Gut symptoms are the least specific in medicine. Bloating can be insufficient stomach acid or too much fermentation; those are opposite problems with opposite answers, and treating one as the other is why people spend ye…

The Detox & Liver Support Blueprint
Four arms — and the first honest point is that you already have a detox system

Clearing a compound happens in stages, and supporting the wrong one makes things worse rather than better. Phase I modifies the molecule — often making it *more* reactive. Phase II conjugates it to something wat…

Hormones

Two different blueprints, because the questions are not the same one.

The Testosterone Blueprint
16 weeks, five arms, one pick each

The single most useful thing to understand here is that low testosterone is a symptom, not a diagnosis. The axis has several points of failure and they need opposite responses: a pituitary signaling problem, a testic…

The Female Hormone Blueprint
16 weeks, five arms, one pick each

Female hormonal complaints get lumped together and they are not one problem. PCOS is fundamentally an insulin and androgen problem that shows up as a cycle problem. **Perimenopause is a declining and erratic estrogen…

Perform and recover

Training capacity, and getting back from an injury.

The Endurance Blueprint
Four arms, and three of them are legal in competition

Endurance fails in four different places and they feel almost identical from the inside. Your mitochondria are too few or too inefficient — that is the biogenesis arm, and it is the one training itself works on. **O…

The Injury Repair Blueprint
12 weeks, five arms, one pick each

Repair is not one process, and the arm that matters depends on which step is stalled. Blood supply is the usual limiter in tendon and ligament, which is why they heal so much slower than muscle. Collagen synthesis is lim…

The Joints & Bone Blueprint
Three arms — two for the joint, one for the skeleton under it

Joint pain has two separable causes and they need different things. The matrix is degrading — cartilage, collagen, the structural substrate — which is slow, and where the substrate arm lives. **The synovium is inflam…

Play the long game

The markers that decide how the next thirty years go.

The Longevity Blueprint
Ongoing, six arms, one pick each

This is the goal with the widest gap between what is exciting and what is evidenced, and being straight about that is the whole value of the page. Five of the six arms below are mechanism-led: nutrient sensing, NAD+, se…

The Cardiovascular Blueprint
Five arms — and most people only need two of them

Cardiovascular risk is not one number and it is certainly not cholesterol alone. Five separable things drive it, and the interventions do not substitute for each other. How many atherogenic particles are circulating…

The Metabolic Health Blueprint
Four arms, four different reasons a number is high

Insulin resistance is not one defect. Four different things produce the same lab pattern, and the intervention that works depends entirely on which one you have. Your cells stopped listening to the fuel signal — tha…

The Immune Resilience Blueprint
Five arms — and two of them point in opposite directions

"Boosting immunity" is not a coherent goal. The immune system is several systems, and the useful question is which part of yours is underperforming. The adaptive arm — T cells, trained by a thymus that physically sh…

The Cognition Blueprint
12 weeks, six arms, one pick each

"Cognition" is not one thing, and that is why most nootropic stacks disappoint. Attention, memory encoding, verbal fluency, processing speed and mood-driven motivation run on different systems — and the compound that fix…

The Bioregulator Blueprint
Two courses a year, five arms, one pick each

Khavinson peptides are very short amino acid sequences — often just two to four — each associated with one tissue. The proposed mechanism is that they act as **signaling molecules telling a specific tissue to normalize i…

Before anything else

If you are not sure where to start, it is this one.

The Foundations Blueprint
Four arms — and the honest answer is about five things

Almost everyone starting out buys in the wrong order. They buy the interesting thing before the boring thing, and they buy a multivitamin instead of finding out what they are actually short of. **The correct order is: f…

None of these quite you?

Every blueprint here is built around a common situation. If yours is complicated — several things at once, bloodwork that disagrees with itself, or a protocol that stopped working — that is what one-on-one coaching is for. If you just want the week-by-week detail behind these, that lives in Skool at $10/mo.

Between the two: fifteen minutes with Cam is $75, which is usually enough to settle which of these is yours — or to hear that none of them is.

Open the Vault · The Bloodwork Vault

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