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The Injury Repair Blueprint

12 weeks, five arms, one pick each

5pathways, one pick each
25options to swap or stack
12week schedule
7markers to draw first

Everything on this page is free. The stack, why each pick beat its alternatives, every option, the bloodwork and the safety lines. The week-by-week schedule and the decision rules are the members half.

Built on 237 compounds and 350 supplements · 1,469 members · 92% stay past month one

Repair is not one process, and the arm that matters depends on which step is stalled. Blood supply is the usual limiter in tendon and ligament, which is why they heal so much slower than muscle. Collagen synthesis is limited by substrate and by timing rather than by signalling. And inflammation is not the enemy — it is the first phase of repair, and suppressing it is one of the most common ways people slow their own healing down. The five arms below map onto those steps. Pick by which one is actually stuck.

Research protocol

This is a theoretical research protocol written for the research community. The compounds below are supplied for research purposes and are not approved medicines — several are not approved for human use in any jurisdiction. Nothing here is medical advice, a prescription, or a recommendation for human use, and it has not been evaluated by the FDA. Full disclaimer & affiliate disclosure →

Who this is forSomeone with a soft-tissue injury that is healing slowly — tendon, ligament, muscle or gut lining. If you have not had it looked at, do that first. Nothing on this page distinguishes a strained tendon from a partial tear, and the two need opposite amounts of loading.
How these combine

Can you run all of them? Not this time - and here is why

These are anatomically specific, not additive. A bone peptide does nothing for a hamstring and a gut-lining compound does nothing for a tendon. Running all five for one strain is money spent on tissue you have not injured. Match the arm to the tissue, then stack freely within it.

This is a general protocol. You make the final call on how much of it to run — or have it built around your labs.

Start here

Which of these 5 is actually you?

This tells you where your biggest leverage is — where to start, not where to stop. Read the But line too: it is what each lane cannot do for you, which is the part a list of options never tells you.

1
Angiogenesis & cytoprotection
Something has been sore for months and is not getting better. The injury itself has healed; the tissue has not.
But Almost all of the evidence here is animal. The mechanism is real, the human data is anecdote.
2
Collagen & matrix synthesis
It is a tendon or a ligament, and it is the same one every time. Loading it is what sets it off.
But Slow by nature. Tendon remodels over months, and nothing shortens that - the supplements only remove a bottleneck.
3
Inflammation resolution (not suppression)
It is swollen, hot and angry, and you have been living on ibuprofen to train through it.
But Suppressing inflammation blocks the signal your body repairs with. This lane RESOLVES rather than blocks - which is slower and does not feel like a painkiller.
4
Gut lining & mucosal repair
Months of NSAIDs, or gut symptoms that arrived with the injury and never left.
But Does nothing for the joint itself. This is here because the treatment caused a second problem, not because it fixes the first.
5
Bone & fracture healing
A confirmed fracture or a stress reaction, or a DEXA result you were not expecting.
But Bone remodels on a decade-scale cycle. This is judged in years and by scan, not by feel.

Before any of it — the foundation

These four are not a disclaimer at the bottom of the page. They are the reason the rest of it works, and every one of them is free.

Sleep — 7–9 h, consistent timing

Growth hormone is released in pulses during deep sleep, insulin sensitivity is measurably worse after one bad night, and appetite regulation collapses without it. Every compound below works through a system that sleep already governs. This is not filler advice — it is the highest-leverage item on the page and it is free.

Protein — 1.6–2.2 g/kg bodyweight daily

The single dietary variable with the most consistent evidence behind it for body composition, in both directions — building and preserving. Under-eating protein while running anything anabolic is paying for a signal with no substrate to act on.

Resistance training — 3–4 sessions weekly, progressive

Nothing here substitutes for mechanical tension. Compounds change how well you recover from and adapt to training; they do not replace the stimulus. A protocol run without training reliably produces the side effects and not the results.

Steps — 8,000–12,000 daily

Non-exercise activity is the largest and most variable component of daily energy expenditure, and it is the one that quietly falls when you start dieting. Tracking it stops the metabolic adaptation people blame on their thyroid.

The stack

How to read thisFive arms, and the right one depends on your injury. A tendon problem is an angiogenesis and collagen problem. A gut-lining problem is a mucosal one. Bone is its own thing entirely. Running all five for a hamstring strain is wasted money. The priority label says where I would start for a typical soft-tissue injury; read the arm names and take the ones that match.
On the evidence

Said once, rather than against every item. This is the research space and human data is limited on most of the peptides here. That is the honest state of the field, not a reason to rank them — unproven is not the same as ineffective. Each option is described by what it does so you can choose on mechanism, and every compound's own page carries its evidence tier in full.

Each pick names what it was chosen over and why. That is the difference between a blueprint and a list — if you disagree with a choice, the alternative is right there and swapping it does not break the rest.

Section 1.1

Peptides 2

Short amino-acid chains that signal rather than force. Almost all are injected or intranasal, they need reconstituting, and they are the reason most people are on this site.

Angiogenesis & cytoprotection
BPC-157 (inj/oral)
The angiogenesis arm

The limiting factor in tendon and ligament healing is blood supply — these tissues are poorly vascularised, which is precisely why they heal so much slower than muscle. BPC-157's proposed mechanism is promoting new vessel growth into the injured area and protecting the cells already there. It is the most-used peptide in this space for a reason.

Start here — it is the arm that unblocks the others
Daily, from week 1
The other lanes in this arm

TB-500 works through actin regulation and cell migration — a different route, which is why the two are routinely run together rather than chosen between. GHK-Cu drives remodelling and is strongest in skin. ARA-290 acts on the innate repair receptor and is aimed at neuropathic pain more than structural repair. Actovegin improves oxygen and glucose uptake in the tissue. BPC-157 is the base because vascularisation is usually the actual bottleneck, and because it is the one with the broadest reported use across tissue types.

Stack this arm deeper6 optional add-ons

Each of these sits in this same pathway, so it starts the week this pathway starts. Swapping one in for the pick above does not change the schedule.

TB-500

Actin regulation and cell migration — it helps repair cells GET to the site, where BPC-157 helps supply reach it. Genuinely complementary rather than additive, which is why the pairing is the standard one in this space.

The trade-off Long half-life, so it accumulates across a course rather than clearing between doses. Same unresolved proliferation question as everything in this class.

GHK-Cu (inj/oral)

Copper peptide — drives matrix remodelling and collagen organisation rather than raw synthesis. Strongest case in skin and scar quality.

The trade-off Systemic copper loading competes with zinc absorption over a long course. If you run it for months, check zinc.

ARA-290

Acts on the innate repair receptor. The distinctive claim here is neuropathic pain and small-fibre function rather than structural healing — a different problem that often travels with injury.

The trade-off If your issue is mechanical rather than neuropathic, this arm is not aimed at you.

Wolverine Blend

BPC-157 and TB-500 together — the two halves of the repair argument in one vial. BPC is local and angiogenic; TB-500 is systemic and works on actin and cell migration. Most people running both end up here anyway.

The trade-off A blend fixes the ratio for you. And you cannot tell which arm did anything, which matters if you are deciding what to repeat.

Actovegin

A deproteinised calf blood extract that improves oxygen and glucose uptake in hypoxic tissue — used in European sports medicine for muscle tears, with an unusually long clinical track record for something in this space.

The trade-off Bovine-derived, with the sourcing questions that implies. Banned in some sporting contexts by injection.

Pentosan Polysulfate

Aimed at cartilage rather than soft tissue — it inhibits the enzymes that degrade the matrix and is licensed for osteoarthritis in animals in several countries.

The trade-off Heparin-like, so it carries a real bleeding risk. Rare reports of pigmentary maculopathy with long-term use.

No vetted source — prescription only. The write-up is still on its page.
Inflammation resolution (not suppression)
KPV
5 options
The inflammation-RESOLUTION arm
How often1x Daily · 5 On 2 Off or Daily
What the mechanism allowsDaily is fine; the short half-life is not the constraint
A brief exposure starts a process that outlasts the molecule. The compound is gone in hours; what it switched on runs for days. Frequency is set by how long that response lasts, which is why the half-life looks alarmingly short and does not matter. Tested at: 5 On 2 Off or Daily.
5 options — 0 to swap in, 5 to stack ontap to collapse
SPMs (Pro-Resolving Mediators)Specialized lipid mediatorsStack on
Concentrated omega-3-derived signaling molecules (resolvins, protectins) that actively switch OFF inflammation and drive tissue resolution — distinct from just supplying fish oil.
How oftenA short course for acute recovery, not a daily supplement
Low Dose NaltrexoneStack on
At 50mg naltrexone is a straightforward opioid antagonist.
How often1x · Nightly
Buy at AlgoRx →code CAMERON
CurcuminMeriva phytosome (SF)Stack on
The active polyphenol of turmeric, in Thorne's phytosome (Meriva) delivery that dramatically improves its otherwise poor absorption.
How oftendaily
BoswelliaPhytosomeStack on
Frankincense extract standardized to boswellic acids, in an absorption-enhanced phytosome, targeting the 5-LOX inflammatory pathway (distinct from NSAIDs' COX pathway).
How oftenDaily
BromelainPineapple enzymeStack on
A pineapple-derived proteolytic enzyme for protein digestion (with food) and anti-inflammatory/recovery support (empty stomach).
How oftenDaily during recovery; per meal for digestion
The most important thing on this page is what NOT to take. NSAIDs — ibuprofen, naproxen — suppress the inflammatory phase that the repair cascade depends on, and there is reasonable evidence they impair tendon and bone healing specifically. That does not make them never appropriate; uncontrolled pain that stops you sleeping or loading the tissue is its own problem, and sleep is where repair happens. But taking them by default for weeks, on the assumption that less inflammation is better, is working directly against arm three — and it is what most people do. If you need pain control, paracetamol does not have the same anti-inflammatory action. That is a conversation worth having with whoever is treating the injury.
Section 2

Health supplements & substrate

The floor underneath the compounds. Cheap, well tolerated, and the part that decides whether anything above it has a fair chance — a secretagogue on a magnesium deficiency is a rounding error.

Collagen & matrix synthesis
Gelatin + Vitamin C
6 options
The collagen substrate arm
How oftenPer session, on days you load the tendon
6 options — 0 to swap in, 6 to stack ontap to collapse
CollagenPeptides (+ cofactors)Stack on
Hydrolyzed collagen peptides that supply the amino-acid building blocks (glycine, proline, hydroxyproline) for skin, joint and connective tissue, often paired with vitamin C.
How oftendaily
Vitamin CAscorbic acid / BufferedStack on
Water-soluble antioxidant and essential cofactor for collagen synthesis, immune cells and neurotransmitter production.
How oftenDaily, split if you go above 1 g
UC-II CollagenUndenatured type II collagenStack on
Mechanistically distinct from ordinary collagen peptides — it works at a fortieth of the dose, and not by supplying building blocks.
How oftendaily
GlycineFree-form amino acidStack on
A simple, sweet-tasting amino acid that acts as an inhibitory neurotransmitter, a building block of collagen and glutathione, and a mild body-temperature regulator for sleep.
How oftenDaily
MSMMethylsulfonylmethaneStack on
A bioavailable sulfur compound that supplies raw material for collagen and connective tissue, with anti-inflammatory benefits for joints and skin/hair.
How oftenDaily
CopperBisglycinateStack on
An essential trace mineral for iron metabolism, connective tissue, and antioxidant enzymes — important to balance against long-term zinc use.
How oftenDaily
Gut lining & mucosal repair
L-Glutamine
4 options
The gut-lining arm
How oftenDaily
4 options — 0 to swap in, 4 to stack ontap to collapse
Zinc CarnosinePepZin GIStack on
A zinc-and-carnosine complex that adheres to and heals the stomach and gut lining — excellent for ulcers, gastritis and leaky gut.
How oftenTwice daily
ButyrateTributyrin / Na-K butyrateStack on
The primary short-chain fatty acid that fuels colon cells — the postbiotic your gut bacteria normally make from fiber, supplied directly.
How oftenDaily
ColostrumBovine colostrumStack on
The nutrient- and antibody-rich 'first milk,' packed with immunoglobulins, lactoferrin and growth factors for gut-lining and immune support.
How oftenDaily
DGL LicoriceDeglycyrrhizinated licoriceStack on
Licorice with the blood-pressure-raising glycyrrhizin removed — soothes the stomach and supports the mucosal lining for reflux and ulcers.
How oftenPer meal, chewed
Bone & fracture healing
Vitamin D
4 options
The bone arm
How oftenDaily
4 options — 0 to swap in, 4 to stack ontap to collapse
Vitamin K2 Complex3-K Complete (K1/MK-4/MK-7)Stack on
A full vitamin-K complex (K1 plus MK-4 and MK-7 forms of K2) that activates the proteins directing calcium into bone and away from arteries.
How oftenDaily
Calcium & MagnesiumMalateStack on
Bone-supporting minerals in the well-absorbed malate form, balanced together (calcium and magnesium work as a pair).
How oftenDaily, split
BoronBoron glycinate/citrateStack on
A trace mineral with an outsized effect on hormones — it raises free testosterone and free estrogen by lowering SHBG, and supports bone and vitamin-D metabolism.
How oftenDaily
CollagenPeptides (+ cofactors)Stack on
Hydrolyzed collagen peptides that supply the amino-acid building blocks (glycine, proline, hydroxyproline) for skin, joint and connective tissue, often paired with vitamin C.
How oftendaily

The 12-week schedule

What goes in, what comes out, and when. The exact doses for each phase are inside the Academy — the structure below is free because it is the part you need to decide whether this fits your life.

1–45–89–1213–1617+
BPC-157 (inj/oral)
Gelatin + Vitamin C
SPMs (Pro-Resolving Mediators)
Vitamin C
TB-500

Each bar is a week block that compound is running. The shape is free — it is what tells you whether this fits your life. The doses for each phase are the members half.

Weeks 1–4
Acute — supply and resolution

Get blood supply and substrate in, and stop suppressing the inflammatory phase.

Loading matters more than any compound here. The substrate arm only builds collagen if a mechanical signal tells it where — that is what the 30–60 minute timing before rehab work is for. Compounds with no loading produce nothing but expense.

Weeks 5–8
Remodelling

The tissue is laying down matrix. The job is organising it, which means progressive load.

Increase load gradually and keep the pre-load substrate timing. If pain is sharp rather than sore, back off — sharp is information, not weakness.

Weeks 9–12
Return to capacity

Rebuild tolerance to the loads that caused the problem.

Most reinjury happens here, because the tissue feels fine before it is capable. Tendon remodels over months. Feeling better is not the same as being ready, and this is the phase where a general protocol most needs a human watching it.

Weeks 13–16
Rebuild capacity, not just tissue

Load it deliberately while the repair arms are still running.

Tissue heals to the demand placed on it. A tendon repaired in a sling heals disorganised; the same tendon under progressive load lays collagen down along the line of force. This is the phase where the compounds stop being the intervention and the loading starts.

Weeks 17+
Return to load, not to comfort

Pain-free is not the same as healed.

Tendon and ligament remodel for months after the pain stops, and reinjury clusters in exactly that window because it feels finished. Progress load deliberately for at least as long again as the protocol ran.

The doses for each phase are inside

Every compound above, dosed week by week, plus the reconstitution numbers and Coach Cam's notes on running it. $10/mo.

Unlock the schedule →

Bloodwork

Short panel, because injury repair has fewer useful markers than the other blueprints — and pretending otherwise would be padding. Vitamin D is the one that changes what you do. Deficiency genuinely impairs bone and soft-tissue healing, it is extremely common, and it is trivially cheap to correct. Testing it is worth more than everything else on this list. hs-CRP tracks whether systemic inflammation is settling. HbA1c matters because poorly controlled glucose measurably slows healing — if an injury is not resolving and nobody has checked it, that is a real miss.

Before you start

Everything, drawn before you start. This is the one that decides which pathway is actually yours - and the only one you cannot go back and collect later.

hs-CRP (High-Sensitivity C-Reactive Protein)Vitamin D (25-Hydroxy)Comprehensive Metabolic Panel (CMP)Complete Blood Count (CBC) with DifferentialFerritinHbA1c (Hemoglobin A1c)TSH (Thyroid-Stimulating Hormone)
Order the Baseline panel →7 markers · about $84 at list · code CAMERON auto-applies

Around week 8

The short list, drawn while you are running it. Not a progress report - it is the draw that catches the things that go wrong quietly.

hs-CRP (High-Sensitivity C-Reactive Protein)Vitamin D (25-Hydroxy)
Order the Mid-cycle safety check panel →2 markers · about $38 at list · code CAMERON auto-applies

After

Drawn at the end, against your own baseline. This is what turns the protocol into information rather than a feeling.

hs-CRP (High-Sensitivity C-Reactive Protein)Vitamin D (25-Hydroxy)Comprehensive Metabolic Panel (CMP)
Order the Re-test panel →3 markers · about $48 at list · code CAMERON auto-applies

All three are drawn at Quest, 2,000+ US locations, no doctor visit, HSA/FSA eligible. Prefer to pick and choose? Every marker above links to its own page, and the panel builder assembles any combination.

Adjusting it

A protocol you cannot adjust is a protocol you abandon. Four situations come up on nearly every run of this — nausea that will not settle, a three-week stall, hair shedding, glucose moving the wrong way. Each one has a specific answer, and the wrong answer to a stall is the reason most people end up on six compounds that each do nothing.

The four decision rules are inside

What to change, what to leave alone, and how to tell a real stall from a water shift. $10/mo.

Unlock the decision rules →

The lines I'd stop at

This is a general protocol, and that is deliberate.

It is built for the common case, not for you specifically. Compound selection and dosing genuinely do change person to person — training age, bloodwork, what you have run before, what you react to. Adjust it against your own numbers using the panels above, or if you want it built around your labs rather than the average, that is what 1-on-1 coaching is for.

See every option for this goal → · Open the Vault