The Bioregulator Blueprint
Two courses a year, five arms, one pick each
Everything on this page is free. The stack, why each pick beat its alternatives, every option, the bloodwork and the safety lines. The week-by-week schedule and the decision rules are the members half.
Khavinson peptides are very short amino acid sequences — often just two to four — each associated with one tissue. The proposed mechanism is that they act as signaling molecules telling a specific tissue to normalize its own gene expression, rather than supplying anything the tissue is short of. That is a genuinely different idea from every other page on this site, and it is why the dosing convention is so unusual: microgram-to-milligram amounts, ten days on, then months off. You are sending a signal, not maintaining a level. Pick by the tissue you actually want to work on. Running six at once is the commonest mistake and it makes the result impossible to read.
Can you run all of them? Not this time - and here is why
This is a general protocol. You make the final call on how much of it to run — or have it built around your labs.
Which of these 5 is actually you?
This tells you where your biggest leverage is — where to start, not where to stop. Read the But line too: it is what each lane cannot do for you, which is the part a list of options never tells you.
Before any of it — the foundation
These four are not a disclaimer at the bottom of the page. They are the reason the rest of it works, and every one of them is free.
Growth hormone is released in pulses during deep sleep, insulin sensitivity is measurably worse after one bad night, and appetite regulation collapses without it. Every compound below works through a system that sleep already governs. This is not filler advice — it is the highest-leverage item on the page and it is free.
The single dietary variable with the most consistent evidence behind it for body composition, in both directions — building and preserving. Under-eating protein while running anything anabolic is paying for a signal with no substrate to act on.
Nothing here substitutes for mechanical tension. Compounds change how well you recover from and adapt to training; they do not replace the stimulus. A protocol run without training reliably produces the side effects and not the results.
Non-exercise activity is the largest and most variable component of daily energy expenditure, and it is the one that quietly falls when you start dieting. Tracking it stops the metabolic adaptation people blame on their thyroid.
The stack
This needs saying more directly here than anywhere else on the site. The evidence base for this entire category is almost exclusively one research group's, mostly published in Russian, and rarely replicated independently. That is not a reason to dismiss it — Khavinson's group has decades of work and some of it is long-duration — but it is a reason to treat any course as an experiment you measure rather than a protocol you trust. Unproven is not the same as ineffective. It is also not the same as proven, and this is the page where that distinction does the most work.
Each pick names what it was chosen over and why. That is the difference between a blueprint and a list — if you disagree with a choice, the alternative is right there and swapping it does not break the rest.
Bioregulators 5
The Khavinson school, in two forms: short synthetic peptides of two to four amino acids, and polypeptide fractions extracted from one animal organ and taken as capsules, tablets or injections. Each is proposed to act on the tissue it is named for, and all of them are dosed as courses months apart rather than continuously. The most speculative class here, and the page says so.
The thymus physically shrinks with age — it is one of the few organs where the decline is visible on a scan — and immune competence tracks that involution. Thymalin is the peptide with the most of this research group's own long-duration data behind it, including trials reporting reduced mortality in elderly cohorts over multi-year follow-up.
Thymogen is a shorter fragment aimed at the same tissue. Vladonix is the thymus complex. Crystagen spans immune and CNS. Thymosin Alpha 1 is the outlier in this arm — it is not a Khavinson peptide at all, it is a 28-amino-acid peptide with real Western clinical use in hepatitis B and as a vaccine adjuvant. Thymalin is the base because it has the most of the group's own long-duration work. If you want the option with independent Western evidence, that is Thymosin Alpha 1 — and it is below rather than above only because it is a different category of thing.
Stack this arm deeper4 optional add-ons
Each of these sits in this same pathway, so it starts the week this pathway starts. Swapping one in for the pick above does not change the schedule.
Not a bioregulator — a genuinely clinically used peptide with independent Western trials, licensed in several countries for hepatitis B and used as a vaccine adjuvant. If you want immune support with evidence that does not depend on one research group, this is it.
The trade-off More expensive, and it is an immune MODULATOR — the direction of effect in autoimmune conditions is not straightforwardly good.
The thymus complex of the Khavinson set, aimed at the same target as Thymalin.
The trade-off Overlaps almost entirely with Thymalin — pick one, running both is duplication.
Spans immune and CNS targets rather than one tissue.
The trade-off Dual-target makes it harder to attribute any result to, which cuts against the whole point of running one at a time.
A shorter dipeptide fragment aimed at the same thymic tissue — the minimal-sequence version of the Thymalin argument.
The trade-off Even less independent data than Thymalin. Overlaps almost entirely, so run one.
Brain & pinealEpitalon4 options
4 options — 0 to swap in, 4 to stack ontap to collapse
Endocrine & reproductiveEndoluten5 options
5 options — 0 to swap in, 5 to stack ontap to collapse
Vascular, cardiac & structuralChelohart4 options
4 options — 0 to swap in, 4 to stack ontap to collapse
Liver, kidney, gut & lungSvetinorm5 options
5 options — 0 to swap in, 5 to stack ontap to collapse
Bacteriostatic water
26 of the compounds in this stack ship as a freeze-dried powder and have to be reconstituted before they are anything. Bacteriostatic water is the diluent — sterile water with 0.9% benzyl alcohol, which is what lets a vial be drawn from more than once. It does not come with the vial, and it is the one item on this page you will buy again every time. Work out your dilution →
Running several vials at once? Flawless Compounds sells a vial case — optional, but it is what keeps a fridge shelf of half-used vials from becoming a guessing game.
Health supplements & substrate
The floor underneath the compounds. Cheap, well tolerated, and the part that decides whether anything above it has a fair chance — a secretagogue on a magnesium deficiency is a rounding error.
The 12-week schedule
Phase one is below in full, free, so you can see exactly what starting looks like — 2 come out before the end. What changes, and when, is the part you are paying for — and it is what decides whether 12 weeks of effort compounds or just runs in parallel.
Ten days. Measure before and after.
Bloodwork before the course, not after it starts. This is a category where the effect is subtle enough that without a baseline you will simply believe whatever you expected to believe.
Months off is the protocol, not a break from it.
Repeat, and use the same measures.
Twice yearly at most, and only if it earned it.
Twice yearly at most, and only if it earns it.
The rest of the schedule is inside Skool
- The remaining 4 phases in full — what each one is for and what it changes
- The dose for every item in every phase — they are not the same across phases, and that is the point
- What comes out, when, and what happens if you leave them in
- The 5 decision rules — what to change when it is not working, and how to tell a real stall from noise
Everything above this line is free and stays free — the compounds, why each one is here, what to test, and the lines I would stop at. Each compound’s dose is free on its own page too. What you cannot get anywhere else is the order, and the order is what decides whether 12 weeks of effort compounds or just runs in parallel. That is the half worth paying for, so that is the half behind the door.
Unlock the schedule — $10/mo →Bloodwork
Bloodwork is not optional on this page — it is the only thing separating an experiment from a belief. Nothing here produces a reliable feeling, and this is the category most prone to expectation doing the work. Match the panel to the arm. Immune → CBC with differential, particularly lymphocytes. Liver → ALT, AST and GGT on the CMP. Kidney → eGFR and creatinine, with cystatin C if you are muscular. Prostate → baseline PSA before anything. Cardiac and vascular → ApoB and hs-CRP. Draw before the course and again 4–6 weeks after it ends. If nothing moved across two courses, that is a real answer.
Before you start
Everything, drawn before you start. This is the one that decides which pathway is actually yours - and the only one you cannot go back and collect later.
Around week 8
The short list, drawn while you are running it. Not a progress report - it is the draw that catches the things that go wrong quietly.
After
Drawn at the end, against your own baseline. This is what turns the protocol into information rather than a feeling.
All three are drawn at Quest, 2,000+ US locations, no doctor visit, HSA/FSA eligible. Prefer to pick and choose? Every marker above links to its own page, and the panel builder assembles any combination.
Adjusting it
A protocol you cannot adjust is a protocol you abandon. 5 situations come up on nearly every run of this — nothing happened, you want to run it continuously, which peptide for a problem that spans tissues and considering the oral capsules instead of injectable, and 1 more. Each one has a specific answer, and the wrong answer to a stall is the reason most people end up on six compounds that each do nothing.
The 5 decision rules are inside
The situations above, each with what to change, what to leave alone, and how to tell a real stall from noise. $10/mo.
Unlock the decision rules →The lines I'd stop at
- Any injection-site reaction that is spreading, hot, or worsening after 48 hours. That is infection rather than irritation.
- A new lump, or a mole that changes. Nothing here is established as causing that — and nothing in this category is worth running while an unexplained finding is unexplained.
- Any new symptom that started with a course and has not settled a month after it ended. The whole model says the effect should be transient; something persisting is worth taking seriously.
- Any injection-site reaction that is spreading, hot, or worsening after 48 hours.
- A new lump, or a mole that changes. Nothing here is established as causing that, and no speculative category is worth running while an unexplained finding is unexplained.
It is built for the common case, not for you specifically. Compound selection and dosing genuinely do change person to person — training age, bloodwork, what you have run before, what you react to. Adjust it against your own numbers using the panels above, or if you want it built around your labs rather than the average, that is what 1-on-1 coaching is for. Between the two: fifteen minutes with Cam is $75.
See every option for this goal → · Open the Vault