The Detox & Liver Support Blueprint
Four arms — and the first honest point is that you already have a detox system
Everything on this page is free. The stack, why each pick beat its alternatives, every option, the bloodwork and the safety lines. The week-by-week schedule and the decision rules are the members half.
Clearing a compound happens in stages, and supporting the wrong one makes things worse rather than better. Phase I modifies the molecule — often making it *more* reactive. Phase II conjugates it to something water-soluble so it can leave, and it is the step that is actually rate-limited by nutrition. Phase III exports it. Then it enters bile, and a share of it gets reabsorbed from the gut and does the whole loop again — which is where the binder arm earns its place. The fourth arm is alcohol, which deserves its own because acetaldehyde is a specific problem with specific cofactors. Inducing Phase I without Phase II capacity increases reactive intermediates. That is the actual mechanism by which a badly designed detox protocol causes harm.
Can you run all of them? Yes - and here is what it costs
This is a general protocol. You make the final call on how much of it to run — or have it built around your labs.
Which of these 4 is actually you?
This tells you where your biggest leverage is — where to start, not where to stop. Read the But line too: it is what each lane cannot do for you, which is the part a list of options never tells you.
Before any of it — the foundation
These four are not a disclaimer at the bottom of the page. They are the reason the rest of it works, and every one of them is free.
Growth hormone is released in pulses during deep sleep, insulin sensitivity is measurably worse after one bad night, and appetite regulation collapses without it. Every compound below works through a system that sleep already governs. This is not filler advice — it is the highest-leverage item on the page and it is free.
The single dietary variable with the most consistent evidence behind it for body composition, in both directions — building and preserving. Under-eating protein while running anything anabolic is paying for a signal with no substrate to act on.
Nothing here substitutes for mechanical tension. Compounds change how well you recover from and adapt to training; they do not replace the stimulus. A protocol run without training reliably produces the side effects and not the results.
Non-exercise activity is the largest and most variable component of daily energy expenditure, and it is the one that quietly falls when you start dieting. Tracking it stops the metabolic adaptation people blame on their thyroid.
The stack
Split this page in half and the two halves have very different standing. Real: NAC is the hospital treatment for paracetamol overdose and its glutathione mechanism is not in question. Sulforaphane's induction of Nrf2 and Phase II enzymes is well characterized. TUDCA and UDCA are used clinically in cholestatic liver disease. Thiamine repletion in alcohol use is standard medicine. Thin: the binder arm. Activated charcoal works acutely in poisoning and its chronic use is largely unevidenced. Zeolite, bentonite and chlorella have heavy-metal-contamination concerns of their own — several products have tested positive for the metals they claim to remove. And nothing here treats a diagnosed liver disease.
Each pick names what it was chosen over and why. That is the difference between a blueprint and a list — if you disagree with a choice, the alternative is right there and swapping it does not break the rest.
Bacteriostatic water
3 of the compounds in this stack ship as a freeze-dried powder and have to be reconstituted before they are anything. Bacteriostatic water is the diluent — sterile water with 0.9% benzyl alcohol, which is what lets a vial be drawn from more than once. It does not come with the vial, and it is the one item on this page you will buy again every time. Work out your dilution →
Running several vials at once? Flawless Compounds sells a vial case — optional, but it is what keeps a fridge shelf of half-used vials from becoming a guessing game.
Health supplements & substrate
The floor underneath the compounds. Cheap, well tolerated, and the part that decides whether anything above it has a fair chance — a secretagogue on a magnesium deficiency is a rounding error.
Phase II conjugation — the step that actually clears thingsSulforaphane (Crucera-SGS)5 options
5 options — 0 to swap in, 5 to stack ontap to collapse
Hepatocyte protection & liver functionTUDCA6 options
6 options — 0 to swap in, 6 to stack ontap to collapse
Binders & interrupting reabsorptionPsyllium Husk5 options
5 options — 0 to swap in, 5 to stack ontap to collapse
Alcohol, acetaldehyde & recoveryNAC6 options
6 options — 0 to swap in, 6 to stack ontap to collapse
The 12-week schedule
Phase one is below in full, free, so you can see exactly what starting looks like — one more item arrives later. What changes, and when, is the part you are paying for — and it is what decides whether 12 weeks of effort compounds or just runs in parallel.
CMP, CBC, GGT, hs-CRP, and heavy metals only if there is a real exposure history.
This is the step that distinguishes this page from the industry it sits in. Raised ALT and AST are almost always fatty liver or alcohol, and both have specific answers that are not on this page. GGT is the marker most sensitive to alcohol specifically. Do not run a provoked or challenge heavy metal test — they produce alarming numbers by design and are not a recognized diagnostic.
Sulforaphane and NAC. Nothing dramatic.
TUDCA with meals. Fiber daily.
CMP and GGT. Compare against baseline, not against how you feel.
Cruciferous vegetables, fiber, less alcohol, less visceral fat.
The rest of the schedule is inside Skool
- The remaining 4 phases in full — what each one is for and what it changes
- Which phase the one later item arrives in, and why it waits instead of starting on day one
- The dose for every item in every phase — they are not the same across phases, and that is the point
- The 5 decision rules — what to change when it is not working, and how to tell a real stall from noise
Everything above this line is free and stays free — the compounds, why each one is here, what to test, and the lines I would stop at. Each compound’s dose is free on its own page too. What you cannot get anywhere else is the order, and the order is what decides whether 12 weeks of effort compounds or just runs in parallel. That is the half worth paying for, so that is the half behind the door.
Unlock the schedule — $10/mo →Bloodwork
GGT is the marker on this page and it is not on every basic panel — ask for it. It is the most sensitive routine indicator of alcohol intake and of biliary problems, and it moves before ALT does. ALT above roughly 30 in a man or 20 in a woman suggests fatty liver even inside the stated reference range — those ranges were derived from populations that already had it. An AST-to-ALT ratio above 2 points at alcohol specifically. Ferritin is here for two reasons: it rises with inflammation and liver injury, and hemochromatosis is a common genetic cause of liver damage that gets missed for decades. Ceruloplasmin covers the copper side — Wilson's disease is rare, treatable, and devastating if missed in a young person with unexplained liver enzymes. Only draw heavy metals if there is a genuine exposure history, and never as a provoked test.
Before you start
Everything, drawn before you start. This is the one that decides which pathway is actually yours - and the only one you cannot go back and collect later.
Around week 8
The short list, drawn while you are running it. Not a progress report - it is the draw that catches the things that go wrong quietly.
After
Drawn at the end, against your own baseline. This is what turns the protocol into information rather than a feeling.
All three are drawn at Quest, 2,000+ US locations, no doctor visit, HSA/FSA eligible. Prefer to pick and choose? Every marker above links to its own page, and the panel builder assembles any combination.
Adjusting it
A protocol you cannot adjust is a protocol you abandon. 5 situations come up on nearly every run of this — ALT is raised and nothing here moved it, you feel worse after starting, A hair or provoked urine test showed high metals and you want this for hormone or estrogen clearance, and 1 more. Each one has a specific answer, and the wrong answer to a stall is the reason most people end up on six compounds that each do nothing.
The 5 decision rules are inside
The situations above, each with what to change, what to leave alone, and how to tell a real stall from noise. $10/mo.
Unlock the decision rules →The lines I'd stop at
- Yellowing of the skin or eyes, dark urine, or pale stools. That is jaundice and it needs same-day assessment, not a supplement.
- Confusion, tremor or disorientation in anyone with known liver disease. That is hepatic encephalopathy.
- Vomiting blood, or black tarry stools. Variceal bleeding is an emergency.
- Any new right upper abdominal pain with fever.
- Withdrawal symptoms on stopping alcohol — tremor, sweating, hallucinations or seizure — are medically dangerous. Stopping heavy long-term drinking without supervision can be fatal, and that is the opposite of the usual advice for a reason.
It is built for the common case, not for you specifically. Compound selection and dosing genuinely do change person to person — training age, bloodwork, what you have run before, what you react to. Adjust it against your own numbers using the panels above, or if you want it built around your labs rather than the average, that is what 1-on-1 coaching is for. Between the two: fifteen minutes with Cam is $75.
See every option for this goal → · Open the Vault