🌡️ Adrenal & Cortisol Axis

For everyone · 8 markers · $216.90 with code CAMERON ~~$241.00~~

Wired-and-tired, crashing mid-afternoon, salt cravings, dizzy on standing, or you've been told you have 'adrenal fatigue'.

🩸 Order this exact panel — 10% off

All 8 markers load into your cart in one click. No doctor's visit, drawn at any Quest location in the US, results by email in about two weeks. Code CAMERON applies automatically.

Add all 8 markers — $216.90 → Open the full Bloodwork Vault →

Why this panel

'Adrenal fatigue' isn't a recognised diagnosis, but the symptoms people describe are real and several genuinely measurable conditions produce them. This panel tests for the ones that actually exist.

💡 What most people missThe point of this panel is to find the real thing instead of the internet thing. Three findings change management completely and none of them are 'tired adrenals': (1) low morning cortisol with a high ACTH points to the adrenal gland itself and is genuine adrenal insufficiency — a medical diagnosis needing treatment. (2) Low cortisol with a low or normal ACTH points upstream to the pituitary, which is a different workup entirely. (3) High aldosterone with low potassium is primary aldosteronism, the most common curable cause of high blood pressure — and it is massively underdiagnosed. A single cortisol reading can't distinguish any of these, which is why cortisol alone is close to useless here.

⏰ When to get it drawnCortisol and ACTH must be drawn 7–9am — both follow a steep daily rhythm and an afternoon draw is uninterpretable. Fasted. Off biotin 72 hours. If you're on hydrocortisone or prednisone, tell whoever ordered the test.

What's inside

This panel covers 8 markers chosen for this specific situation. The full list, the clinical reasoning behind each marker, draw timing and how to interpret your results are available to Academy members.

🔒 Panel and protocol are inside the Academy

Every marker and why it's here — plus the full evidence-graded Adrenal & Cortisol Axis protocol: why ‘adrenal fatigue’ isn’t the answer and what is — the cortisol/ACTH pairing that separates an adrenal problem from a pituitary one, the curable cause of high blood pressure almost nobody screens for, and the supplements that make it worse. $10/mo, cancel anytime.

Unlock the full panel →

Free marker breakdowns

These explainers are free: what each one measures, the optimal range rather than just the lab range, and what actually moves it.

DHEA-S Pregnenolone Aldosterone ACTH (Adrenocorticotropic Hormone)DHEA

Frequently asked questions

What blood tests are in the Adrenal & Cortisol Axis panel?

8 markers: Cortisol, ACTH, DHEA-S, Pregnenolone, Aldosterone, Comprehensive Metabolic Panel (CMP), TSH (Thyroid-Stimulating Hormone), Ferritin.

How much does the Adrenal & Cortisol Axis panel cost?

$241.00 before discount, $216.90 with code CAMERON applied automatically. Individual markers add a one-time $10 draw fee. Ordered through Marek Diagnostics and drawn at any Quest Diagnostics location in the US.

Do I need a doctor's order for these tests?

No. These are ordered direct-to-consumer through Marek Diagnostics — you order online, walk into a Quest location, and results are emailed to you in about two weeks. No physician visit or insurance required. Not available in NY, NJ or RI.

When should I get the Adrenal & Cortisol Axis panel drawn?

Cortisol and ACTH must be drawn 7–9am — both follow a steep daily rhythm and an afternoon draw is uninterpretable. Fasted. Off biotin 72 hours. If you're on hydrocortisone or prednisone, tell whoever ordered the test.

Important: This page is education only, not medical advice and not a diagnosis. A panel is a starting point for a conversation with a clinician, not a substitute for one. Reference ranges vary by laboratory and assay — always compare against the range printed on your own report.