Fertility & egg quality
One of 5 mechanistic pathways to 🌸 Female hormonal balance · 13 options
Oocyte quality depends heavily on mitochondrial function — the egg carries all the mitochondria the embryo will start with, and they have been sitting since before you were born. That is why mitochondrial and antioxidant support dominates this pathway.
Thyroid antibodies belong on this list even with a normal TSH — they independently raise miscarriage risk, and they are routinely left off fertility workups.
Anti-Müllerian Hormone (AMH)LH & FSHEstradiol, Standard (ECLIA)ProgesteroneTSH (Thyroid-Stimulating Hormone)Thyroid Antibodies (TPO + TgAb)Vitamin D (25-Hydroxy)FerritinFolate, RBC🤍 Fertility & Trying to Conceive covers these in one panel →
What engages this pathway
Ordered by how directly each one acts on the mechanism above — never by how much trial evidence exists. Each links to its full breakdown with dosing, half-life and vendor.
🧬 CoQ10
The best-evidenced supplement for oocyte quality. Trials show improved response and embryo quality, particularly in women over 35 — the mitochondrial argument is direct.
🧬 Ubiquinol
The reduced form, better absorbed as conversion capacity falls with age.
🧬 Myo-Inositol
Improves oocyte quality and IVF outcomes in PCOS-specific trials.
🧬 NAC
Improves ovulation and reduces oxidative stress in follicular fluid.
🧬 Methylfolate (5-MTHF)
Neural-tube-defect prevention is the established indication, and the active form matters for those with MTHFR variants.
🧬 Prenatal
The full micronutrient package, started ideally three months before conception since follicular development takes about that long.
🧬 Vitamin D
Status correlates with IVF success rates; deficiency is worth correcting first.
🧬 Omega-3 (Fish Oil)
DHA for foetal neural development, and improved ovarian response in some trials.
🧬 Iron Complex
Pre-conception iron status matters for both fertility and pregnancy outcome.
🧬 Calcium AKG
AKG improved ovarian reserve markers in mouse studies. Very early, mechanistically interesting.
🧬 NMN
NAD+ decline is implicated in oocyte ageing, and mouse work shows restored fertility with precursor supplementation. No human data — one of the more exciting untested extrapolations in the Vault.
🧬 Melatonin
A potent antioxidant that concentrates in follicular fluid; trials show improved oocyte quality in IVF.
🧬 Royal Jelly
Traditional fertility use with animal data on ovarian function.
The other 4 routes to female hormonal balance
Pick the pathway that matches where you are actually stuck. An appetite drug does nothing for someone who already undereats.
Want the protocols behind these?
Dosing schedules, stacking, cycle timing and Coach Cam's notes live inside the Academy — plus the full interactive Vault.
Join the Academy — $10/mo →← Open this pathway in the interactive Vault
Frequently asked questions
Oocyte quality depends heavily on mitochondrial function — the egg carries all the mitochondria the embryo will start with, and they have been sitting since before you were born. That is why mitochondrial and antioxidant support dominates this pathway.
13 options are mapped to this pathway in the Vault, including CoQ10, Ubiquinol, Myo-Inositol, NAC. They are grouped by the mechanism they act through rather than ranked by how much trial evidence exists — 10 carry clinical validation and 3 are mechanistic predictions.
Thyroid antibodies belong on this list even with a normal TSH — they independently raise miscarriage risk, and they are routinely left off fertility workups. The markers worth checking are Anti-Müllerian Hormone (AMH), LH & FSH, Estradiol, Standard (ECLIA), Progesterone.
Unproven is not the same as ineffective. Of the 13 options on this pathway, 10 have clinical validation and 3 are graded theoretical — meaning the mechanism is sound but the specific human trial has not been run, which is true of a great deal of what works in this space. Nothing on this page is ordered by evidence tier, because sorting by trial count would bury the compounds you came looking for.