TMAO (Trimethylamine N-oxide)
A metabolite produced when gut bacteria process choline, carnitine and betaine from food — then converted by the liver.
An emerging cardiovascular risk marker linking gut microbiome composition to atherosclerosis. Notable because it's one of the few markers directly reflecting how your gut bacteria are behaving.
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Order this test — 10% off → Browse all 102 markers →What TMAO (Trimethylamine N-oxide) is usually tested alongside
On its own, one marker is a data point. These panels include TMAO (Trimethylamine N-oxide) plus the markers that make it interpretable — each names every test, why it is on the list, and loads the whole set into your cart in one click at 10% off.
includes this + 8 more markers — Family history of clots, stroke or early heart attack; on testosterone or oestrogen; long-haul travel; or a standard lipid panel that looked fine and you don't believe it.
What moves your TMAO (Trimethylamine N-oxide)
1 compound and 1 supplement in the Vault have a documented effect on this marker, or are a reason to have measured it first:
Browse all 237 compounds & 350 supplements →
Would you feel it? Symptoms TMAO (Trimethylamine N-oxide) helps explain
People rarely search for a marker — they search for how they feel. These are the complaints where this marker is worth checking, and whether it is a first-line test or a follow-up once the obvious causes are ruled out.
Why your TMAO (Trimethylamine N-oxide) might be wrong
Most abnormal results are interference, not disease. These are the things that measurably move this specific marker — check them before you change anything. Each one says whether the number is wrong and should be repeated, badly timed and should be redrawn, or real with a cause worth explaining.
TMAO is produced by gut bacteria from choline and carnitine — red meat, eggs and fish. A single meal shifts it, and fish raises it sharply without the cardiovascular implication red meat carries.
Standardise your diet for 48 hours, and avoid fish for 24 hours before — otherwise the result is meaningless.
Suppress the gut bacteria that make TMAO, producing an artificially low result for weeks.
Wait at least a month after antibiotics.
What TMAO (Trimethylamine N-oxide) means in combination
A single marker tells you a little. Combinations tell you the story — these are the named patterns this marker takes part in, and what each one points at.
Two mechanisms a standard lipid panel cannot see. ADMA inhibits nitric oxide synthase and marks endothelial dysfunction, which precedes plaque by years. TMAO is produced by gut bacteria from choline and carnitine and links the microbiome to arterial risk.
Read ADMA against kidney function — it is renally cleared and rises with impairment. For TMAO, standardise diet for 48 hours and avoid fish for 24, because fish raises it sharply without the same implication.
What to test next
Markers rarely answer alone. These are the ones that put TMAO (Trimethylamine N-oxide) in context — each with its own full breakdown.
Frequently asked questions
<6.2 µmol/L (assay dependent) Ranges vary by laboratory and assay — always compare to the range printed on your own report.
Optimal ranges, root causes and the full correction protocol are available inside Coach Cam's Peptide Academy.
See the full breakdown inside the Academy.
See the full breakdown inside the Academy.
You can order TMAO (Trimethylamine N-oxide) directly through Marek Diagnostics without a doctor's visit — drawn at any Quest Diagnostics location in the US. Code CAMERON applies 10% off automatically.