Metabolic calculator

TyG Index — Insulin Resistance (no insulin needed)

Estimates insulin resistance from just triglycerides and glucose — useful when you didn't order fasting insulin.

Home › Tools › TyG Index — Insulin Resistance (no insulin needed)
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How this is worked out. TyG = ln(triglycerides mg/dL × fasting glucose mg/dL / 2). Simental-Mendía et al., Metab Syndr Relat Disord 2008.
This is the Ln(TG × glucose) ÷ 2 form of the index, which is the form the commonly quoted 4.49 / 4.68 cutoffs belong to — the other convention in circulation, Ln(TG × glucose ÷ 2), runs on an 8-to-9 scale and its cutoffs are not interchangeable with these. Both inputs in mg/dL, fasted. A useful backup, but fasting insulin remains the better test — order it next time.

The bands on this page

ResultWhat it is called here
under 4.49Insulin sensitive
4.49 to 4.68Borderline
over 4.68Insulin resistance likely

What goes in, and where each number comes from

Every input is a real test. Follow one to see its normal range, its optimal range and what moves it — the calculation is only as good as the numbers you feed it.

What it costs to actually get these numbers

The 2 tests on their own$16.20
The cheapest panel that covers them — The Basics — Start Here (4 markers)$32.40
Order the tests, not the panel. This calculation needs 2 results, and buying them individually is $16.20 cheaper than the smallest panel that happens to contain them. The panel is worth it only if you want the other 2 markers on it too.
Order The Basics — Start Here →

Prices are Marek Diagnostics with the 10% code already applied, and they are what was filed when this page was built — check the cart. Ordering through these links pays a commission at no cost to you.

What could have moved the measurement, not the marker

A wrong number and a real change look identical on a report. These are the reasons a result here can be an artifact of how the blood was drawn or run, and they are worth ruling out before anything else.

assayHemolysis (burst red cells)

Red cells rupturing in the tube spill their contents into the serum. Potassium, LDH, AST and magnesium are far higher inside cells than outside, so a hemolyzed sample reports them falsely high. Caused by a difficult draw, a narrow needle, or shaking the tube.

What to do: The lab usually flags it. If your result is odd and the report mentions hemolysis, that is your answer — repeat the draw.

prepFist clenching and tourniquet time

Clenching your fist pumps potassium out of muscle and can raise a measured potassium enough to trigger a false alarm. A long tourniquet concentrates protein, calcium and everything protein-bound.

What to do: Do not pump your fist. Ask for the tourniquet to come off early. An isolated high potassium with no symptoms is usually this.

timingFasting vs non-fasting

Triglycerides rise substantially after eating; total and HDL cholesterol barely move. Because LDL is usually calculated from triglycerides, a non-fasted draw distorts the LDL too — and the error is worst in exactly the people with high triglycerides.

What to do: Fast 10–12 hours if LDL matters. Guidelines increasingly accept non-fasting lipids, but be consistent between tests.

drugTestosterone and anabolic steroids

Lower HDL substantially, and oral 17-alpha-alkylated compounds do so dramatically.

What to do: Expect it on TRT; note it rather than being alarmed by it in isolation.

4 more interferences are listed on the marker pages themselves: Lipid Panel (Cholesterol, HDL, LDL, Triglycerides) · Comprehensive Metabolic Panel (CMP).

This tool does not diagnose anything. It puts a number next to a published interval and shows the arithmetic that got there. It cannot see your symptoms, your medications, your history or the assay your lab ran. A result outside the outer bounds belongs in front of a clinician, not in a supplement search.

Where to go with this

Read one of these results on its ownType a value, pick your units and sex, and see where it sits and what could have moved it.The Basics — Start Here4 markers, $32.40 with the code — what it settles and what it does not.Every marker on this site103 markers, each with the normal range, the optimal range and what moves it.

The other metabolic calculations

HOMA-IR — Insulin ResistanceThe standard research index of insulin resistance. Catches metabolic dysfunction years before glucose or HbA1c move.QUICKI — Insulin SensitivityA companion to HOMA-IR that some researchers consider more reliable at the low-insulin end. Higher is better here.Estimated Average Glucose (from HbA1c)Converts your HbA1c into the average blood glucose it represents — far more intuitive than a percentage.