Myeloperoxidase (MPO)
An enzyme released by activated white blood cells within arterial plaque, promoting oxidative damage and plaque instability.
Where Lp-PLA2 indicates plaque inflammation, MPO indicates plaque vulnerability — the tendency to rupture, which is what actually causes heart attacks. Complements the structural markers.
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🩸 Test your Myeloperoxidase (MPO)
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Order this test — 10% off → Browse all 102 markers →What Myeloperoxidase (MPO) is usually tested alongside
On its own, one marker is a data point. These panels include Myeloperoxidase (MPO) plus the markers that make it interpretable — each names every test, why it is on the list, and loads the whole set into your cart in one click at 10% off.
includes this + 9 more markers — Persistent aches, slow recovery, autoimmune history, high cardiovascular risk, or a raised CRP that nobody explained.
Would you feel it? Symptoms Myeloperoxidase (MPO) helps explain
People rarely search for a marker — they search for how they feel. These are the complaints where this marker is worth checking, and whether it is a first-line test or a follow-up once the obvious causes are ruled out.
Why your Myeloperoxidase (MPO) might be wrong
Most abnormal results are interference, not disease. These are the things that measurably move this specific marker — check them before you change anything. Each one says whether the number is wrong and should be repeated, badly timed and should be redrawn, or real with a cause worth explaining.
MPO comes from neutrophils, so anything activating them — infection, recent injury, smoking — raises it independently of plaque.
Draw when well and away from illness by two weeks.
Red cells rupturing in the tube spill their contents into the serum. Potassium, LDH, AST and magnesium are far higher inside cells than outside, so a haemolysed sample reports them falsely high. Caused by a difficult draw, a narrow needle, or shaking the tube.
The lab usually flags it. If your result is odd and the report mentions haemolysis, that is your answer — repeat the draw.
What Myeloperoxidase (MPO) means in combination
A single marker tells you a little. Combinations tell you the story — these are the named patterns this marker takes part in, and what each one points at.
Residual inflammatory risk. Plaque forms and destabilises through inflammation as well as lipids, so hitting an ApoB target while CRP stays high leaves a meaningful part of the risk untouched.
Rule out the obvious first — CRP rises with any infection, injury or hard training, so retest rested and well. If it stays up: sleep, visceral fat, periodontal disease, gut health, omega-3s. Persistent unexplained elevation deserves a real workup.
What to test next
Markers rarely answer alone. These are the ones that put Myeloperoxidase (MPO) in context — each with its own full breakdown.
Frequently asked questions
<470 pmol/L (assay dependent) Ranges vary by laboratory and assay — always compare to the range printed on your own report.
Optimal ranges, root causes and the full correction protocol are available inside Coach Cam's Peptide Academy.
See the full breakdown inside the Academy.
See the full breakdown inside the Academy.
You can order Myeloperoxidase (MPO) directly through Marek Diagnostics without a doctor's visit — drawn at any Quest Diagnostics location in the US. Code CAMERON applies 10% off automatically.