Blood & Iron calculator

Transferrin Saturation

The percentage of your iron-carrying capacity that's actually filled — the screening number for both iron deficiency and iron overload.

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How this is worked out. Transferrin saturation % = (serum iron µg/dL / TIBC µg/dL) × 100. The standard definition used by every lab that reports it.
Optimal 25–35%. Persistently >45% with high ferritin warrants hemochromatosis genetic testing. Below 20% suggests iron deficiency — confirm with ferritin.

The bands on this page

ResultWhat it is called here
under 20Low — iron deficiency likely
20 to 25Low-normal
25 to 45Optimal
over 45High — screen for hemochromatosis

What goes in, and where each number comes from

Every input is a real test. Follow one to see its normal range, its optimal range and what moves it — the calculation is only as good as the numbers you feed it.

What it costs to actually get these numbers

The 1 test on their own$8.55
The cheapest panel that covers them — High Ferritin — Overload or Inflammation? (8 markers)$80.10
Order the tests, not the panel. This calculation needs 1 result, and buying it individually is $71.55 cheaper than the smallest panel that happens to contain it. The panel is worth it only if you want the other 7 markers on it too.
Order High Ferritin — Overload or Inflammation? →

Prices are Marek Diagnostics with the 10% code already applied, and they are what was filed when this page was built — check the cart. Ordering through these links pays a commission at no cost to you.

What could have moved the measurement, not the marker

A wrong number and a real change look identical on a report. These are the reasons a result here can be an artifact of how the blood was drawn or run, and they are worth ruling out before anything else.

assayHemolysis (burst red cells)

Red cells rupturing in the tube spill their contents into the serum. Potassium, LDH, AST and magnesium are far higher inside cells than outside, so a hemolyzed sample reports them falsely high. Caused by a difficult draw, a narrow needle, or shaking the tube.

What to do: The lab usually flags it. If your result is odd and the report mentions hemolysis, that is your answer — repeat the draw.

timingTime of day

Serum iron has a genuine diurnal rhythm, typically highest in the morning and falling substantially by evening — swings of 30% or more within one day are normal.

What to do: Morning, fasted, and the same time on any repeat.

drugIron supplement taken that morning

Serum iron peaks a few hours after a dose and can more than double. A panel drawn after your morning tablet measures the tablet.

What to do: Take the last dose at least 24 hours before, ideally leave 5 days.

This tool does not diagnose anything. It puts a number next to a published interval and shows the arithmetic that got there. It cannot see your symptoms, your medications, your history or the assay your lab ran. A result outside the outer bounds belongs in front of a clinician, not in a supplement search.

Where to go with this

Read one of these results on its ownType a value, pick your units and sex, and see where it sits and what could have moved it.The High Ferritin — Overload or Inflammation?8 markers, $80.10 with the code — what it settles and what it does not.Every marker on this site103 markers, each with the normal range, the optimal range and what moves it.