Hormones calculator

Progesterone : Estradiol Ratio (Pg/E2)

The classic 'estrogen dominance' index in women — whether progesterone is adequately balancing estradiol in the luteal phase.

Home › Tools › Progesterone : Estradiol Ratio (Pg/E2)
—
How this is worked out. (Progesterone ng/mL × 1000) / estradiol pg/mL — the ×1000 puts both on pg/mL so the ratio is dimensionless.
Multiply progesterone by 1,000 to match estradiol's units. A commonly used luteal target is 100–500, with under 100 suggesting relative estrogen dominance. Only meaningful on a mid-luteal draw — 7 days after ovulation. Not validated for men or postmenopausal women.

The bands on this page

ResultWhat it is called here
under 100Low — relative estrogen dominance
100 to 200Borderline
200 to 500Optimal luteal balance
over 500High progesterone relative to E2

What goes in, and where each number comes from

Every input is a real test. Follow one to see its normal range, its optimal range and what moves it — the calculation is only as good as the numbers you feed it.

What it costs to actually get these numbers

The 2 tests on their own$33.30

Prices are Marek Diagnostics with the 10% code already applied, and they are what was filed when this page was built — check the cart. Ordering through these links pays a commission at no cost to you.

What could have moved the measurement, not the marker

A wrong number and a real change look identical on a report. These are the reasons a result here can be an artifact of how the blood was drawn or run, and they are worth ruling out before anything else.

assayNot suitable for men or post-menopausal women

Adequate at pre-menopausal female concentrations and unreliable at low ones.

What to do: If you are male or post-menopausal, order the sensitive assay instead.

timingCycle day

Progesterone is near-zero in the follicular phase and peaks about seven days after ovulation. Day 21 is only correct if your cycle is 28 days — in a 35-day cycle, day 21 is before ovulation and will read falsely low.

What to do: Draw 7 days after ovulation, tracked with LH sticks — not on a fixed calendar day.

timingPulsatile release

Secreted in pulses, so even correctly timed values vary considerably.

What to do: One low value with a confirmed LH surge is worth repeating.

timingMenstrual cycle phase

Varies severalfold across a normal cycle, so a result without a cycle day attached is close to uninterpretable.

What to do: Note the cycle day. Day 3 for the follicular baseline; seven days after ovulation for the luteal phase.

This tool does not diagnose anything. It puts a number next to a published interval and shows the arithmetic that got there. It cannot see your symptoms, your medications, your history or the assay your lab ran. A result outside the outer bounds belongs in front of a clinician, not in a supplement search.

Where to go with this

Read one of these results on its ownType a value, pick your units and sex, and see where it sits and what could have moved it.All lab panelsNo single panel carries every input for this one. The panel index lists what each covers.Every marker on this site103 markers, each with the normal range, the optimal range and what moves it.

The other hormones calculations

Free Testosterone (Vermeulen)Calculates free testosterone from total T, SHBG and albumin — far more reliable than direct analog assays.Free Androgen Index (FAI)A quick index of androgen availability from total testosterone and SHBG. Widely used in PCOS assessment in women.Testosterone : Estradiol Ratio (men)Balances your androgen and estrogen signal. Useful when symptoms don't match either value alone.