Liver, kidney, gut & lung
One of 5 mechanistic pathways to 🧬 Organ-specific bioregulation · 9 options
The clearance and barrier organs. Each has its own peptide in the series, which is the clearest illustration of how the whole model works — one tissue, one signal.
Cystatin-C reads kidney function independently of muscle mass, which matters if you're muscular — creatinine systematically overstates decline in that group and understates it in the frail.
Comprehensive Metabolic Panel (CMP)Cystatin C with eGFRUrinalysis, RoutineEnhanced Liver Fibrosis (ELF) Tesths-CRP (High-Sensitivity C-Reactive Protein)🫘 Kidney Health — Read Properly covers these in one panel →
What engages this pathway
Ordered by how directly each one acts on the mechanism above — never by how much trial evidence exists. Each links to its full breakdown with dosing, half-life and vendor.
💉 Livagen
Liver bioregulator; the injectable form of the series' hepatic peptide.
💉 Svetinorm
The oral liver bioregulator from the same series — the peptides are paired injectable-and-oral throughout, with the oral forms assumed rather than shown to survive digestion.
💉 Pielotax
Renal bioregulator, proposed to support glomerular and tubular function. Nothing outside the Russian programme has examined it, and kidney claims deserve particular caution.
💉 Vesilut
Bladder and urinary-tract bioregulator, proposed for age-related urothelial decline. No independent evidence.
💉 Chitomur
Bladder-wall bioregulator from the same series.
💉 Vilon
The thymic dipeptide (Lys-Glu) — one of the most-studied in the programme, with reported effects on immune and gut mucosal tissue.
💉 Chonluten
Lung and bronchial bioregulator, proposed for age-related and inflammatory decline in respiratory tissue.
💉 Bronchogen
The synthetic bronchial tetrapeptide derived from Chonluten's active fragment; same target, same absence of independent replication.
💉 Taxorest
Respiratory bioregulator for bronchial and pulmonary tissue.
The other 4 routes to organ-specific bioregulation
Pick the pathway that matches where you are actually stuck. An appetite drug does nothing for someone who already undereats.
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Frequently asked questions
The clearance and barrier organs. Each has its own peptide in the series, which is the clearest illustration of how the whole model works — one tissue, one signal.
9 options are mapped to this pathway in the Vault, including Livagen, Svetinorm, Pielotax, Vesilut. They are grouped by the mechanism they act through rather than ranked by how much trial evidence exists — 0 carry clinical validation and 9 are mechanistic predictions.
Cystatin-C reads kidney function independently of muscle mass, which matters if you're muscular — creatinine systematically overstates decline in that group and understates it in the frail. The markers worth checking are Comprehensive Metabolic Panel (CMP), Cystatin C with eGFR, Urinalysis, Routine, Enhanced Liver Fibrosis (ELF) Test.
Unproven is not the same as ineffective. Of the 9 options on this pathway, 0 have clinical validation and 9 are graded theoretical — meaning the mechanism is sound but the specific human trial has not been run, which is true of a great deal of what works in this space. Nothing on this page is ordered by evidence tier, because sorting by trial count would bury the compounds you came looking for.