17-OH Progesterone
A steroid intermediate in the adrenal pathway between progesterone and cortisol/androgens.
The screening test for non-classic congenital adrenal hyperplasia (NCAH) — an under-recognized cause of androgen excess that mimics PCOS in women and can cause early androgenic symptoms in men.
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🩸 Test your 17-OH Progesterone
Order directly through Marek Diagnostics — no doctor's visit needed, drawn at any Quest location in the US. Code CAMERON applies 10% off automatically.
Order this test — 10% off → Browse all 102 markers →What 17-OH Progesterone is usually tested alongside
On its own, one marker is a data point. These panels include 17-OH Progesterone plus the markers that make it interpretable — each names every test, why it is on the list, and loads the whole set into your cart in one click at 10% off.
includes this + 10 more markers · built for men — Fatigue, low libido, poor recovery, mood or body composition changes — and you're considering TRT. Read this before you start.
includes this + 10 more markers · built for men — You've decided to start testosterone therapy. Draw this before your first injection.
includes this + 9 more markers · built for women — Irregular or absent periods, acne, unwanted hair growth, scalp thinning, difficulty losing weight, or you've been told 'probably PCOS' without a workup.
includes this + 7 more markers · built for women — Acne along the jawline, chin and neck that flares before your period, persisting or starting in your 20s, 30s or 40s.
Would you feel it? Symptoms 17-OH Progesterone helps explain
People rarely search for a marker — they search for how they feel. These are the complaints where this marker is worth checking, and whether it is a first-line test or a follow-up once the obvious causes are ruled out.
Why your 17-OH Progesterone might be wrong
Most abnormal results are interference, not disease. These are the things that measurably move this specific marker — check them before you change anything. Each one says whether the number is wrong and should be repeated, badly timed and should be redrawn, or real with a cause worth explaining.
Has a marked morning peak and rises substantially in the luteal phase — a luteal draw can look like congenital adrenal hyperplasia when it is simply the wrong week.
Draw early morning, follicular phase (day 3–5). This is one of the easiest markers to misread on timing alone.
Suppress 17-OHP, which can mask the very condition the test is looking for.
Note any steroid use, including inhaled and topical.
What 17-OH Progesterone means in combination
A single marker tells you a little. Combinations tell you the story — these are the named patterns this marker takes part in, and what each one points at.
Points upstream of the ovary. Markedly raised 17-OHP suggests non-classic congenital adrenal hyperplasia, which is routinely mislabelled as PCOS and managed the wrong way for years.
An 8am 17-OHP is the discriminating test — this is worth getting right, because NCAH and PCOS are treated differently. Bring it to an endocrinologist rather than treating it as PCOS by default.
What to test next
Markers rarely answer alone. These are the ones that put 17-OH Progesterone in context — each with its own full breakdown.
Frequently asked questions
<220 ng/dL (adult men) Ranges vary by laboratory and assay — always compare to the range printed on your own report.
Optimal ranges, root causes and the full correction protocol are available inside Coach Cam's Peptide Academy.
See the full breakdown inside the Academy.
See the full breakdown inside the Academy.
You can order 17-OH Progesterone directly through Marek Diagnostics without a doctor's visit — drawn at any Quest Diagnostics location in the US. Code CAMERON applies 10% off automatically.